A profound knowledge of mobile radio channels is required for the development, evaluation, and also assessment at practical conditions of present and future mobile radio communication systems. The modelling, analysis, and simulation of mobile radio channels are important key area in current context. In addition to that, knowledge of channel behaviour in mobile radio communication is extensively recommended for the study of transmitter/receiver performances under different propagation scenarios. Our intention in this research work was to develop various kinds of mobile fading channel simulators using MATLAB and embed them into MATLAB software as a toolbox. Implemented channel simulators were combined MATLAB as a toolbox which users can easily select well-known channel models to test and to study the performance of mobile communication systems. It gives better support for the new users to work on the developed channel simulators, run the test procedures as well as parameter computation. The toolbox contains channel simulators for simulating non-stationary land mobile satellite channel, spatial shadowing processes, MIMO channels, multiple uncorrelated Rayleigh fading channels, mobile to mobile channel, frequency hopping channels etc. Set of test procedures were developed such as the autocorrelation function ACF, average duration of fades ADF, the probability density function PDF, and the level-crossing rate LCR etc., in order to test and to confirm the correctness of the implemented channel simulators. Proposed new algorithms to compute the model parameters of the channel simulators were also implemented in the toolbox to enable the parameterization of the channel simulators under specific propagation conditions. Some of the simulation models were implemented based on specification of GSM system by CEPT-COST 207.